LRRTM1 leucine rich repeat transmembrane neuronal 1 [ (human)]. Gene ID: , updated on 7-Dec This gene is imprinted, being predominantly expressed from the paternal allele and showing a variable pattern of maternal down-regulation. May be associated . Leucine-rich repeat transmembrane neuronal protein 1. Gene. Lrrtm1. Organism. Mus musculus (Mouse). Status. Reviewed-Annotation score: Annotation.

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RCSB PDB – Gene View – LRRTM1 – leucine rich repeat transmembrane neuronal 1

Integrated resource of protein families, domains and functional sites More Mouse A9 cells containing single human chromosomes for analysis of genomic imprinting. Eur J Hum Genet. Transport Classification Database More Lrrtm1 interacts with markers MirMirMirCorresponds to variant dbSNP: Select item s lrdtm1 click on “Add to basket” to create your own collection here entries max.

UCSC genome browser More The Gene Wiki collection of pages on human genes and proteins More Eukaryotic Ortholog Groups More If the zoom level is high ltrtm1, it can show the nucleotides at the corresponding location, or a graphical encoding for each nucleotide A: It is useful for tracking sequence updates.

Initially detected at 9 dpc with expression present in the overlying ectoderm of the limb bud in the presumptive apical ectodermal ridge.

Heritability of lobar brain volumes in twins supports genetic models of lrrtk1 laterality and handedness. Show all Align All. ProteomicsDB human proteome resource More Non-supervised Orthologous Groups More H-Invitational Database, human transcriptome db More Handedness, brain asymmetry and schizophrenia are likely to be etiologically complex traits with several, or many, genetic and environmental influences.


Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

In addition, expression within the human thalamus was more restricted as compared to the mouse, with staining relatively limited to dorsomedial regions. BioMuta curated single-nucleotide variation and disease association database More It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.

June 21, Last sequence update: These results suggest that endogenous LRRTM1 genw have a role lrrt,1 intracellular trafficking within axons. We are determined to keep this website freely accessible.

Supplementary Figure S5 jpeg 54K Click here to view. Leucine-rich repeat transmembrane n Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2pq Nogo and the Nogo receptor. The receptor-like structure of LRRTM1 also suggests that it may be a drug-tractable target in its own right. Molecular Grne carbohydrate derivative binding cytoskeletal protein binding DNA binding enzyme regulator hydrolase ligase lipid binding oxidoreductase RNA binding signaling receptor activity signaling receptor binding transcription transferase transporter.

Localized morphological brain differences between English-speaking Caucasians and Chinese-speaking Asians: Abstract Left—right asymmetrical brain function underlies much of human cognition, behavior and emotion. Select item s and click on “Add to basket” to create your own collection here entries max.

Lrrtm1 MGI Mouse Gene Detail – MGI – leucine rich repeat transmembrane neuronal 1

PaxDb, a database of protein ltrtm1 averages across all three domains of life More Live-cell staining for overexpressed LRRTM1 in DRG neurons revealed that the protein is not accessible on the plasma membrane under conditions that allowed surface detection of a related member of the LRR protein superfamily, Lingo1 Figure 5.


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Early asymmetry of gene transcription in embryonic human left and right cerebral cortex. These various submissions may originate gens different sequencing projects, different types of experiments, or different biological samples.

We screened the first two exons and predicted promoter of LRRTM1 for polymorphisms in 26 left-handers from the RD sample by denaturing high-performance liquid chromatography and sequencing, but we did not detect any polymorphisms that tagged rsrsrs haplotypeor that had overt disruptive effects on the predicted LRRTM1 protein entirely coded within exon 2.

This is the first potential genetic influence on gne handedness to be identified, and the lrttm1 putative genetic effect on variability in human brain asymmetry.

LRRTM1 – leucine rich repeat transmembrane neuronal 1

Please consider making a donation now and again in the future. Polymorphic imprinting of the serotonin-2A 5-HT2A receptor gene gen human adult brain. GXD’s primary emphasis is on endogenous gene expression during development.